What is the best initial response for a PN when a patient's medication appears different than expected?

The best initial response when a patient's medication appears different than expected is to verify with the pharmacy. This action is essential because it prioritizes patient safety and ensures that the right medication is being administered. Medications can vary in appearance due to several factors, including manufacturer differences, formulations, or potential errors in dispensing.

By confirming with the pharmacy, the practical nurse can determine if the medication is indeed correct, check for any recent changes in the medication formulation, or identify if there has been a mistake in the dispensing process. This step is crucial in preventing potential medication errors that could harm the patient.

Administering the medication as it is without verification poses a risk, as the nurse would not have confirmed its appropriateness or safety. Advising the patient not to worry could diminish their trust and not address the legitimate concern regarding medication discrepancies. Changing the medication to match what the patient has at home undermines the established protocol and could lead to administering the wrong medication. Therefore, verifying with the pharmacy is the most responsible and safest course of action.